Diseases caused by Leishmania present a worldwide problem, and current therapeutic
approaches are unable to achieve a sterile cure. Leishmania is able to persist in host cells
by evading or exploiting host immune mechanisms. A thorough understanding of these
mechanisms could lead to better strategies for effective management of Leishmania
infections. Current research has focused on parasite modification of host cell signaling
pathways, entry into phagocytic cells, and modulation of cytokine and chemokine profiles …